The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Dec. 05, 2019
Applicant:

Tillotts Pharma Ag, Rheinfelden, CH;

Inventors:

Felipe Varum, Rheinfelden, CH;

Laetitia Von Rochow, Rheinfelden, CH;

Carsten Markus Füller, Rheinfelden, CH;

Roberto Carlos Bravo González, Rheinfelden, CH;

Assignee:

Tillotts Pharma AG, Rheinfelden, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/2893 (2013.01); A61K 9/0053 (2013.01); A61K 9/2013 (2013.01); A61K 9/2054 (2013.01); A61K 9/2059 (2013.01); A61K 9/2095 (2013.01); A61K 9/2846 (2013.01); A61K 9/286 (2013.01); A61K 9/2886 (2013.01);
Abstract

A method produces a coatable core for a delayed release drug formulation for oral administration, to deliver a drug to the colon. The method involves forming a core containing a drug. An outer layer coating preparation is formed by combining a first aqueous preparation of an enzymatically degradable polymer, which is degradable by colonic bacterial enzymes; a second aqueous preparation of a film-forming enteric polymer having a pH threshold of about pH 6 or above; and an organic anti-tack agent. The core is then coated with the outer layer coating preparation to form an outer layer coated core.


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