The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2025

Filed:

Jan. 03, 2020
Applicant:

Treeway Tw001 B.v., Rotterdam, NL;

Inventors:

Ronald Van Der Geest, Rotterdam, NL;

Sytske Hyke Moolenaar, Rotterdam, NL;

Assignee:

TREEWAY TW001 B.V., Rotterdam, NL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/08 (2006.01); A61K 9/00 (2006.01); A61K 9/14 (2006.01); A61K 31/4152 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/08 (2013.01); A61K 9/0053 (2013.01); A61K 9/14 (2013.01); A61K 31/4152 (2013.01); A61P 25/28 (2018.01);
Abstract

The present invention relates to the use of a liquid aqueous solution of edaravone in the treatment of an oxidative stress-mediated neurodegenerative disorder in a human patient, said treatment comprising at least once daily oral administration of the liquid edaravone solution to the human patient, to provide a daily dose of 40-120 mg edaravone during an uninterrupted period of at least 10 days. Examples of oxidative stress-mediated neurodegenerative disorders that can be treated in this way include amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), cerebral amyloid angiopathy (CAA), Alzheimer's disease and Parkinson's disease.


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