The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2025

Filed:

Jul. 27, 2020
Applicant:

Verinata Health, Inc., San Diego, CA (US);

Inventor:

Richard P. Rava, Redwood City, CA (US);

Assignee:

VERINATA HEALTH, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16B 20/10 (2019.01); C12Q 1/6883 (2018.01); G16B 30/00 (2019.01); G16B 30/10 (2019.01);
U.S. Cl.
CPC ...
G16B 20/10 (2019.02); C12Q 1/6883 (2013.01); G16B 30/00 (2019.02); G16B 30/10 (2019.02); C12Q 2600/156 (2013.01);
Abstract

The present invention provides a method capable of detecting single or multiple fetal chromosomal aneuploidies in a maternal sample comprising fetal and maternal nucleic acids, and verifying that the correct determination has been made. The method is applicable to determining copy number variations (CNV) of any sequence of interest in samples comprising mixtures of genomic nucleic acids derived from two different genomes, and which are known or are suspected to differ in the amount of one or more sequence of interest. The method is applicable at least to the practice of noninvasive prenatal diagnostics, and to the diagnosis and monitoring of conditions associated with a difference in sequence representation in healthy versus diseased individuals.


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