The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Jun. 28, 2019
Osaka University, Suita, JP;
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Kohji Nishida, Osaka, JP;
Noriyasu Hashida, Osaka, JP;
Tetsuya Iida, Osaka, JP;
Shota Nakamura, Osaka, JP;
Daisuke Motooka, Osaka, JP;
Kazunobu Asao, Osaka, JP;
Satoru Ando, Osaka, JP;
Osaka University, Osaka, JP;
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
A method for detecting conjunctival diseases such as conjunctival MALT lymphoma, and an aging biomarker that serves as an indicator of the aging state of a subject are provided. The method for detecting conjunctival diseases comprises a step of comparing a microbial community structure of a microbiota in an ocular surface tissue specimen sampled from a healthy person with a microbial community structure of a microbiota in an ocular surface tissue specimen sampled from a subject to determine that the ocular surface tissue specimen of the subject has an indication of the conjunctival diseases. The aging biomarker a comprises bacterial species which belongs to the Corynebacteriaceae family or the Propionibacteriales family in an ocular surface tissue.