The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Jan. 28, 2022
Allogene Therapeutics, Inc., South San Francisco, CA (US);
Todd Luman, Hayward, CA (US);
Josergio Zaragoza, Daly City, CA (US);
Abraham Germansderfer, Boca Raton, FL (US);
Suma Rao, San Francisco, CA (US);
Yajin Ni, San Diego, CA (US);
Chupei Zhang, San Francisco, CA (US);
Tom Tao Huang, Fremont, CA (US);
Allogene Therapeutics, Inc., South San Francisco, CA (US);
Abstract
Provided herein are improved methods for transducing immune cells, such as T cells, with retroviral vectors to express exogenous gene products, such as chimeric antigen receptors (CARs). Provided herein are methods that increase transduction efficiency thereby increasing the percentage of immune cells in a population expressing the exogenous gene product. Associated cells, cell populations, compositions and methods of use are also provided.