The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2025

Filed:

May. 29, 2020
Applicant:

Acceleron Pharma Inc., Rahway, NJ (US);

Inventors:

John Knopf, Edgartown, MA (US);

Ravindra Kumar, Acton, MA (US);

Asya Grinberg, Lexington, MA (US);

Dianne Sako, Medford, MA (US);

Roselyne Castonguay, Watertown, MA (US);

Yossi Dagon, Ashland, MA (US);

Jonathan Belk, Lebanon, NH (US);

Nathan J. Sharkey, Lebanon, NH (US);

Assignee:

Acceleron Pharma Inc., Rahway, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 3/04 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61P 3/04 (2018.01); A61K 39/00 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01);
Abstract

This disclosure provides ALK7-binding proteins such as anti-ALK7 antibodies, and compositions and methods for making the ALK7-binding proteins. In certain embodiments, the ALK7-binding proteins inhibit or antagonize ALK7 activity. In addition, the disclosure provides compositions and methods for diagnosing and treating overweight, obesity, diabetes, overweight, obesity, type 2 diabetes, and their associated conditions; metabolic disorders, and other diseases or conditions that can be treated, prevented or ameliorated by targeting ALK7.


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