The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Oct. 09, 2019
Inhibrx Biosciences, Inc., La Jolla, CA (US);
Brendan P. Eckelman, La Jolla, CA (US);
Michael D. Kaplan, La Jolla, CA (US);
Katelyn M. Willis, La Jolla, CA (US);
Rajay A. Pandit, La Jolla, CA (US);
Angelica N. Sanabria, La Jolla, CA (US);
Sydney A. Barnes, La Jolla, CA (US);
Margaret E. Haerr, La Jolla, CA (US);
John C. Timmer, La Jolla, CA (US);
Inhibrx Biosciences, Inc., La Jolla, CA (US);
Abstract
Provided herein are binding polypeptides that specifically bind DLL3. More specifically, provided herein are fusion proteins, including multivalent and/or multispecific contracts and chimeric antigen receptors, that bind DLL3. Also provided are pharmaceutical compositions containing the polypeptides, nucleic acid molecules encoding the polypeptides and vectors and cells thereof, and methods of use and uses of the provided DLL3 binding polypeptides for treating diseases and conditions, such as cancer.