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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12365726 B1

PDFFull Text
Date of Patent:
Jul. 22, 2025

Filed:

Apr. 13, 2023

Anti-vegf antibody constructs

Applicant:

Akouos, Inc., Boston, MA (US);

Inventors:

Emmanuel John Simons, Brookline, MA (US);

Robert Ng, Newton, MA (US);

Michael McKenna, Boston, MA (US);

Assignee:

Akouos, Inc., Boston, MA (US);

Attorneys:

Choate, Hall & Stewart LLP

Stephanie L. Schonewald

Primary Examiner:

Anoop K Singh

Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 48/00 (2006.01); A61P 27/16 (2006.01); C07K 14/005 (2006.01); C07K 14/55 (2006.01); C07K 16/22 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 48/0066 (2013.01); A61P 27/16 (2018.01); C07K 14/005 (2013.01); C07K 14/55 (2013.01); C12N 15/86 (2013.01); C07K 2317/24 (2013.01); C07K 2317/55 (2013.01); C07K 2317/76 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14152 (2013.01);
Abstract

The present disclosure provides a construct comprising a coding sequence operably linked to a promoter, wherein the coding sequence encodes a vascular endothelial growth factor (VEGF) binding agent or a portion thereof. In some embodiments, a construct is an AAV construct. In some embodiments, an AAV construct is a part of an AAV particle. Compositions comprising constructs and AAV particles described herein can be useful in treating hearing loss, for example, hearing loss associated with vestibular schwannoma.

Find Patent Forward Citations

Simons, Emmanuel. (2025). Anti-vegf antibody constructs (U.S. Patent No. 12365726). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12365726

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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