The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Oct. 11, 2024
Abbvie Inc., North Chicago, IL (US);
Mohamed-Eslam F. Mohamed, Gurnee, IL (US);
Ahmed A. Othman, Libertyville, IL (US);
Aileen L. Pangan, La Grange, IL (US);
Ben Klünder, Ludwigshafen, DE;
Heidi S. Camp, Winnetka, IL (US);
Robert J. Padley, Highland Park, IL (US);
Jeffrey W. Voss, Hudson, MA (US);
Cheng Thiam Tan, Grayslake, IL (US);
AbbVie Inc., North Chicago, IL (US);
Abstract
The present disclosure relates to solid-state forms and corresponding pharmaceutical compositions of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, and methods of treatment, including treatment of rheumatoid arthritis and juvenile idiopathic arthritis using the same. The treatment methods generally comprise administering to a patient (e.g., a pediatric patient) a therapeutically effective amount of upadacitinib as a stable liquid pharmaceutical composition or a solid dosage form, at a dose based on patient body weight.