The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2025

Filed:

Nov. 14, 2016
Applicant:

Hangzhou Dac Biotech Co., Ltd., Hangzhou, CN;

Inventors:

Yongxin Robert Zhao, Hangzhou, CN;

Qingliang Yang, Hangzhou, CN;

Yuanyuan Huang, Hangzhou, CN;

Shun Gai, Hangzhou, CN;

Hangbo Ye, Hangzhou, CN;

Linyao Zhao, Hangzhou, CN;

Chengyu Yang, Hangzhou, CN;

Huihui Guo, Hangzhou, CN;

Xiaomai Zhou, Hangzhou, CN;

Hongsheng Xie, Hangzhou, CN;

Haifeng Zhu, Hangzhou, CN;

Yifang Xu, Hangzhou, CN;

Qianqian Tong, Hangzhou, CN;

Junxiang Jia, Hangzhou, CN;

Minjun Cao, Hangzhou, CN;

Wenjun Li, Hangzhou, JP;

Shuihong Gao, Hangzhou, CN;

Zhixiang Guo, Hangzhou, CN;

Lu Bai, Hangzhou, CN;

Chen Li, Hangzhou, CN;

Yanlei Yang, Hangzhou, CN;

Chunyan Wang, Hangzhou, CN;

Zhichang Ye, Hangzhou, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
A61K 47/6803 (2017.08); A61K 47/68031 (2023.08); A61K 47/68035 (2023.08); A61K 47/6829 (2017.08); A61K 47/6831 (2017.08); A61K 47/6855 (2017.08); A61K 47/6863 (2017.08); A61K 47/6883 (2017.08); A61K 47/6889 (2017.08);
Abstract

The present invention relates to linkers having a group of propiolyl, substituted acryl (acryloyl), or disubstituted propanoyl, and using such linkers for the conjugation of compounds, in particular, cytotoxic agents to a cell-binding molecule.


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