The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Jun. 26, 2020
Travere Therapeutics Switzerland Gmbh, Rapperswil-Jona, CH;
The Regents of the University of Colorado, a Body Corporate, Denver, CO (US);
Erez Bublil, Ets Efraim, IL;
Frank Glavin, Belmont, MA (US);
Marcia Sellos-Moura, West Newbury, MA (US);
Jan P. Kraus, Denver, CO (US);
Tomas Majtan, Aurora, CO (US);
Randy Wanner, Martinsried, DE;
Orhan Causevic, Martinsried, DE;
The Regents of the University of Colorado, A Body Corporate, Denver, CO (US);
Abstract
The present disclosure provides formulations for a drug product comprising a PEGylated CBS protein having the amino acid sequence of SEQ ID NO: 1. Dosages and dosing regimens are provided for treatment of homocystinuria in a subject in need thereof. Additionally, the dosages and dosing regimens are also provided to reduce the level of homocysteine (Hcy) or increase the levels of cysteine (Cys) and/or cystathionine (Cth) in a subject in need thereof.