The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Aug. 14, 2020
Duke University, Durham, NC (US);
Sumitomo Pharma Switzerland Gmbh, Basel, CH;
Mary Louise Markert, Durham, NC (US);
Laura P. Hale, Durham, NC (US);
Joanne Kurtzberg, Durham, NC (US);
Lynn Cheatham, Durham, NC (US);
Gregory D. Sempowski, Durham, NC (US);
Andrew N. MacIntyre, Durham, NC (US);
Alex Tracy, Cambridge, MA (US);
Kristin Marks, Cambridge, MA (US);
Karin Pihel, Cambridge, MA (US);
Enzyvant Therapeutics GMBH, Basel, CH;
Duke University, Durham, NC (US);
Abstract
Methods and compositions for promoting donor-specific tolerance and immunocompetence to a recipient of a solid organ transplant, by implanting an allogeneic solid organ in a recipient in need of a solid organ transplant and further comprising surgical implantation of a tissue-engineered allogeneic cultured postnatal thymus tissue product in the recipient of a solid organ from a donor. Methods of producing an allogeneic cultured postnatal thymus tissue-derived product suitable for implantation into a human; methods of culturing allogeneic cultured postnatal thymus tissue-derived product suitable for implantation into a human and methods of using allogeneic cultured postnatal thymus tissue-derived product by implantation in a human subject.