The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Apr. 26, 2022
The Regents of the University of Michigan, Ann Arbor, MI (US);
Tomasz Cierpicki, Ann Arbor, MI (US);
Jolanta Grembecka, Ann Arbor, MI (US);
Huang Huang, Ann Arbor, MI (US);
Sergei Zari, Ann Arbor, MI (US);
Hyo Je Cho, Ann Arbor, MI (US);
Mykhaylo Potopnyk, Ann Arbor, MI (US);
Sergii Dudkin, Ann Arbor, MI (US);
Wenbing Chen, Ann Arbor, MI (US);
Yassir Adam, Ann Arbor, MI (US);
Christina Howard, Ann Arbor, MI (US);
EunGi Kim, Ann Arbor, MI (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
Abstract
Provided herein are small molecule inhibitors of NSD1, NSD2 and/or NSD3 activity, and methods of use thereof for the treatment of disease, including leukemia, breast cancer, osteosarcoma, lung and prostate cancers and other solid tumors as well as other diseases dependent on the activity of NSD1, NSD2 and/or NSD3.