The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Sep. 12, 2024
Applicant:

Academy of Military Medical Sciences, Beijing, CN;

Inventors:

Wenwen Xin, Beijing, CN;

Lin Kang, Beijing, CN;

Jiaxin Li, Beijing, CN;

Tingting Liu, Beijing, CN;

Lina Dong, Beijing, CN;

Shan Gao, Beijing, CN;

Jinglin Wang, Beijing, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 21/64 (2006.01); G01N 33/543 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); G01N 21/6428 (2013.01); G01N 33/54326 (2013.01); G01N 33/582 (2013.01); G01N 2021/6439 (2013.01); G01N 2333/42 (2013.01);
Abstract

A rapid detection method for abrin toxin is provided. The rapid detection method for abrin toxin includes the following steps: reacting an oligonucleotide chain substrate labeled with a fluorescent group and a quenching group, a buffer solution, a BSA solution, a to-be-detected sample and sterile water, incubating at a constant temperature, detecting a fluorescence signal value, and determining whether the abrin toxin exists based on a difference between a change in final fluorescence signal value and a change in final fluorescence signal value of a negative control; where the sample is judged as a positive sample when an average value of the detected final fluorescence signal values is greater than an average value of the final fluorescence signal values of the negative control by +3 times standard deviation. According to the detection method, the direct addition of the sample into the reaction system can reach the sensitivity of 30 ng/mL.


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