The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Jun. 22, 2018
Applicants:

Institut National Des Sciences Appliquees DE Toulouse, Toulouse, FR;

Universite Toulouse Iii-paul Sabatier, Toulouse, FR;

Centre National DE LA Recherche Scientifique, Paris, FR;

Institut National DE LA Recherche Agronomique, Paris, FR;

Inventors:

Stéphanie Heux, Balma, FR;

Alessandro De Simone, Bari, IT;

Jean-Charles Portais, Pibrac, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12N 9/04 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/52 (2013.01); C12N 9/0006 (2013.01); C12N 9/1022 (2013.01); C12Y 101/01244 (2013.01); C12Y 202/01001 (2013.01);
Abstract

Disclosed is a microorganism, which has been engineered to acquire methylotrophy. More particularly, the application describes a non-naturally occurring microorganism, which has been engineered to express or include a first enzyme and a second enzyme, wherein the first enzyme is a methanol dehydrogenase (Mdh) enzyme or a methanol oxidase (Mox) enzyme, and wherein the second enzyme is a dihydroxyacetone synthase (Das) enzyme or a transketolase enzyme. The application also describes element and applications, more particularly kits and methods, which include or use the microorganism.


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