The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Jan. 06, 2022
American Gene Technologies International Inc., Rockville, MD (US);
Tyler Lahusen, Rockville, MD (US);
Mei-Ling Liou, Rockville, MD (US);
Lingzhi Xiao, Rockville, MD (US);
Haishan Li, Rockville, MD (US);
Charles David Pauza, Rockville, MD (US);
AMERICAN GENE TECHNOLOGIES INTERNATIONAL INC., Rockville, MD (US);
Abstract
A composition for treating cancer is disclosed. The composition includes a lentiviral particle and an aminobisphosphonate drug. The lentiviral particle is capable of infecting a target cell, such as a cancer cell, and includes an envelope protein optimized for targeting such target cell and a viral vector. The viral vector includes a small RNA optimized to target an FDPS mRNA sequence. The aminobisphosphonate drug includes zoledronic acid.