The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Jul. 15, 2024
Avidity Biosciences, Inc., San Diego, CA (US);
Beatrice Diana Darimont, San Diego, CA (US);
Usue Etxaniz Irigoien, San Diego, CA (US);
Venkata Ramana Doppalapudi, San Diego, CA (US);
Michael Caramian Cochran, La Jolla, CA (US);
Isaac Marks, San Diego, CA (US);
Tyler Albin, San Diego, CA (US);
AVIDITY BIOSCIENCES, INC., San Diego, CA (US);
Abstract
Disclosed herein are antibody oligonucleotide conjugates and pharmaceutical compositions that induce an alteration in an incorrectly spliced dystrophin mRNA transcript to induce exon 44 skipping. Also described herein include methods for treating muscle dystrophy including Duchenne muscular dystrophy that comprises administering antibody oligonucleotide conjugates or a pharmaceutical composition that induces alteration in an incorrectly spliced dystrophin mRNA transcript to induce exon 44 skipping.