The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Sep. 09, 2022
Applicant:

Illumina, Inc., San Diego, CA (US);

Inventors:

M. Shane Bowen, Encinitas, CA (US);

Dajun Yuan, San Diego, CA (US);

Assignee:

ILLUMINA, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); B82Y 15/00 (2011.01); B82Y 20/00 (2011.01); B82Y 30/00 (2011.01); B82Y 40/00 (2011.01); C12Q 1/6816 (2018.01); C12Q 1/6818 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/6874 (2018.01); G01N 21/64 (2006.01); G03F 7/00 (2006.01); G01N 21/05 (2006.01); G01N 21/76 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1093 (2013.01); B82Y 15/00 (2013.01); B82Y 20/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6874 (2013.01); G01N 21/6452 (2013.01); G01N 21/648 (2013.01); G01N 21/6486 (2013.01); G03F 7/0002 (2013.01); B01J 2219/00317 (2013.01); G01N 21/05 (2013.01); G01N 2021/6419 (2013.01); G01N 2021/6441 (2013.01); G01N 21/6456 (2013.01); G01N 21/76 (2013.01);
Abstract

A structured substrate includes a substrate body having an active side. The substrate body includes reaction cavities that open along the active side and interstitial regions that separate the reaction cavities. The structured substrate includes an ensemble amplifier positioned within each of the reaction cavities. The ensemble amplifier includes a plurality of nanostructures configured to at least one of amplify electromagnetic energy that propagates into the corresponding reaction cavity or amplify electromagnetic energy that is generated within the corresponding reaction cavity.


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