The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

May. 13, 2022
Applicant:

Hiroshima University, Hiroshima, JP;

Inventors:

Takashi Yamamoto, Kure, JP;

Tetsushi Sakuma, Higashihiroshima, JP;

Hiroshi Ochiai, Higashihiroshima, JP;

Shinya Matsuura, Hiroshima, JP;

Tatsuo Miyamoto, Hiroshima, JP;

Assignee:

Hiroshima University, Hiroshima, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 9/22 (2006.01); C12N 15/63 (2006.01); C40B 40/08 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); C12N 15/63 (2013.01); C40B 40/08 (2013.01); C07K 2319/80 (2013.01);
Abstract

The present invention provides an artificial nuclease comprising a DNA-binding domain and a function domain linked to each other via a polypeptide consisting of 35 to 55 amino acid residues wherein amino acid residues at two sites in a DNA-binding module contained in a DNA-binding domain exhibit a mode of repetition that is different for every four DNA-binding modules; a vector for expressing said artificial nuclease; a vector library for preparing said vector; and a vector set for preparing said vector library.


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