The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Apr. 23, 2021
The Charles Stark Draper Laboratory Inc., Cambridge, MA (US);
Brett Isenberg, Newton, MA (US);
Joseph Charest, Jamaica Plain, MA (US);
Corin Williams, Framingham, MA (US);
Ernest Kim Soonho, Cambridge, MA (US);
Morgan Pilkenton, Sommerville, MA (US);
Patrick Davis, Sommerville, MA (US);
Elizabeth Ellen Marr, Brookline, MA (US);
Else Marie Vedula, Stoneham, MA (US);
Abstract
The systems and methods of the present disclosure provide highly deformable porous membrane culture systems and actuation methods for studying the effects of biomedical stretch on cultured tissue. A well plate can include a well having a first opening configured to receive an insert coupled to a deformable membrane. The well plate can include a gasket positioned within the well and configured to create a seal between the insert and the well when the insert is positioned in the well. The well plate can include a chamber defined beneath the well, the chamber configured to receive fluid media and to expose the fluid media to a surface of the deformable membrane when the insert is positioned in the well. The well plate can include an actuator configured to stretch the deformable membrane by a target amount of strain.