The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Nov. 19, 2021
Horizon Therapeutics Ireland Dac, Dublin, IE;
David Madden, Mount Kisco, NY (US);
Kathleen Gabriel, Voorhees, NJ (US);
Guido Magni, Basel, CH;
Richard Woodward, Phoenixville, PA (US);
Shao-Lee Lin, Lake Forest, IL (US);
Jeffrey W. Sherman, Lincolnshire, IL (US);
HORIZON THERAPEUTICS IRELAND DAC, Dublin, IE;
Abstract
The invention provides a method of treating or reducing the severity of thyroid-associated ophthalmopathy (TAO), also known as thyroid eye disease (TED) or Graves' ophthalmopathy or orbitopathy (GO), or a symptom or aspect thereof, in subjects that have undergone prior treatment for TAO, TED, or GO, and either did not respond to said prior treatment or relapsed after said prior treatment. The invention also provides antibodies, or antigen binding fragments thereof, and pharmaceutical compositions useful in the disclosed methods.