The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Mar. 23, 2020
Suzhou Kanova Biopharmaceutical Co., Ltd., Jiangsu, CN;
Beijing Kanova Biopharmaceutical Co., Ltd., Beijing, CN;
SUZHOU KANOVA BIOPHARMACEUTICAL CO., LTD., Suzhou, CN;
BEIJING KANOVA BIOPHARMACEUTICAL CO., LTD., Beijing, CN;
Abstract
The present invention is related to anti-B7S1 (B7-H4) polypeptides including anti-B7S1 (B7-H4) antibodies and their immunoreactive fragments, chimeric antigen receptor (CAR) binding to B7S1 (B7-H4) molecule and the uses thereof, particularly in the treatment of cancers. The invention particularly concerns humanized anti-B7S1 antibodies and their antigen binding fragments capable of enhancing the activation of the immune system against diseased tissues including cancerous cells, and the genetically engineered immune cells expressing anti-B7S1 CAR used for treatment of diseases including cancers.