The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

May. 13, 2020
Applicant:

Glaxosmithkline Intellectual Property (No. 2) Limited, Stevenage, GB;

Inventors:

Kent E. Goklen, King of Prussia, PA (US);

Eric J. Suda, Holly Springs, NC (US);

Antonio Raul Ubiera, King of Prussia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); B01D 15/38 (2006.01); C07K 1/22 (2006.01); C07K 16/06 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); B01D 15/3809 (2013.01); C07K 16/065 (2013.01); C07K 2317/569 (2013.01);
Abstract

A method for purifying a protein comprising an antibody, antibody fragment, or immunoglobulin single variable domain, from a solution containing at least one contaminant by superantigen chromatography comprising: a) adsorbing the protein to the superantigen immobilized on a solid support; b) removing the at least one contaminant by contacting the immobilized superantigen containing the adsorbed protein with a first wash buffer comprising an aliphatic carboxylate; and c) eluting the protein from the superantigen immobilized on the solid support.


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