The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Mar. 06, 2020
Virginia Commonwealth University, Richmond, VA (US);
Umesh R. Desai, Richmond, VA (US);
Balaji Nagarajan, Richmond, VA (US);
Connor O'Hara, Richmond, VA (US);
Daniel Kwame Afosah, Richmond, VA (US);
Elsamani I. Abdelfadiel, Richmond, VA (US);
Jyothi Sistla, Richmond, VA (US);
Rahaman Navaz Gangji, Richmond, VA (US);
Ravikumar Ongolu, Richmond, VA (US);
Shravan Morla, Richmond, VA (US);
Viji Sankaranarayanan, Richmond, VA (US);
Bhaumik B. Patel, Richmond, VA (US);
Chetna Sharon, Richmond, VA (US);
Rio Boothello, Richmond, VA (US);
Alberto Vera, Richmond, VA (US);
Virginia Commonwealth University, Richmond, VA (US);
Abstract
A group of specific sulfated flavonoid agents carrying cholesterol modification display promising in vivo anti-cancer activity through selective inhibition of cancer stem cells, and not of adult or hematopoietic stem cells. The compounds exhibit high potency, excellent oral bioavailability and a physiologically relevant therapeutic window.