The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Sep. 24, 2020
Applicant:
Portland State University, Portland, OR (US);
Inventors:
Robert M. Strongin, Portland, OR (US);
Jorge O. Escobedo Cordova, Portland, OR (US);
Tendai Mafireyi, Portland, OR (US);
Assignee:
Portland State University, Portland, OR (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 493/10 (2006.01); C12Q 1/26 (2006.01); G01N 21/29 (2006.01); G01N 21/64 (2006.01); G01N 21/78 (2006.01);
U.S. Cl.
CPC ...
C07D 493/10 (2013.01); C12Q 1/26 (2013.01); C12Y 108/01009 (2013.01); G01N 21/29 (2013.01); G01N 21/6428 (2013.01); G01N 21/78 (2013.01);
Abstract
Seminaphthofluorophore-selenium probes are disclosed. The probes include a seminaphthofluorophore scaffold substituted with at least one diselenide moiety having a formula —Y—C(Q)O—(CH)—Se—Se—(CH)—OR, where Ris hydrogen or C-Calkyl, Q is O or S, Y is O or N(R) where Ris H or alkyl, and m and n independently are integers. The probes may be used to detect presence of a thioredoxin reductase.