The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Aug. 25, 2021
Applicant:

Nantong University, Jiangsu, CN;

Inventors:

Hong Dai, Jiangsu, CN;

Heyi Miao, Jiangsu, CN;

Meiling Huang, Jiangsu, CN;

Cheng Qian, Jiangsu, CN;

Dandan Zheng, Jiangsu, CN;

Yan Zhang, Jiangsu, CN;

Yang Wang, Jiangsu, CN;

Yong Ling, Jiangsu, CN;

Beibei Zhou, Jiangsu, CN;

Haijun Zhang, Jiangsu, CN;

Assignee:

NANTONG UNIVERSITY, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61P 31/00 (2018.01); A61P 35/00 (2018.01);
Abstract

The disclosure relates to a preparation method and use of a pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit. The pyrazole compound is prepared by reacting pyrazole aldehyde and 1-(3,4-dimethoxyphenyl)-β-carboline acylhydrazine. The pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit has good inhibitory activity against tumor cell HGC-27. The pyrazole compound could be used in the preparation of anti-tumor drugs.


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