The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Jul. 28, 2023
Applicant:

Bracco Imaging S.p.a., Milan, IT;

Inventors:

Mauro Botta, Turin, IT;

Lorenzo Tei, Turin, IT;

Fabio Carniato, Alessandria, IT;

Zsolt Baranyai, Trieste, IT;

Mariangela Boccalon, Terzo d'Aquileia, IT;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 255/02 (2006.01); A61K 49/10 (2006.01);
U.S. Cl.
CPC ...
C07D 255/02 (2013.01); A61K 49/106 (2013.01);
Abstract

The invention relates to the novel compounds of formula (I) as well as ions, stereoisomers, tautomers, hydrates, solvates, pharmaceutically acceptable salts thereof, or mixtures of the same. The compounds of formula (I) are ligands that are able to chelate Fe(III) ions, thereby generating Fe(III) complexes, which are particularly suitable in diagnostic imaging, for example as contrast agents for magnetic resonance imaging (MRI), due to their high relaxivity, thermodynamic stability, kinetic inertness and redox stability.


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