The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Jun. 16, 2020
Applicant:

Ucb Pharma Gmbh, Monheim, DE;

Inventors:

Cécile Pegurier, Brussels, BE;

Silvia Lovera, Brussels, BE;

Christa E. Mueller, Bonn, DE;

Joerg Hockemeyer, Bonn, DE;

Mahmoud Rashed, Cairo, EG;

Ali El-Tayeb, Bonn, DE;

Yong-Qiang Zhang, Shandong, CN;

Assignee:

UCB Pharma GMBH, Monheim, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/30 (2006.01); A61P 25/28 (2006.01); C07D 401/12 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 209/30 (2013.01); A61P 25/28 (2018.01); C07D 401/12 (2013.01); C07D 471/04 (2013.01);
Abstract

Disclosed are N-(phenyl)-1H-indole-3-sulfonanmide and N-(phenyl)-1H-pyrrolo[2,3-b]pyridine-3-sulfonamide derivatives of formula I substituted at the 1- and 6-positions of the 1H-indole or 1H-pyrrolo[2,3-b]pyridine moiety, as well as structurally related compounds (e.g. the N-pyridin-2-yl and the N-pyridin-3-yl analogues thereof). The present compounds have GPR17 modulating properties which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating disorders such as multiple sclerosis.


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