The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Jul. 07, 2021
Applicant:

Research Triangle Institute, Research Triangle Park, NC (US);

Inventors:

Yanan Zhang, Apex, NC (US);

Thuy Nguyen, Morrisville, NC (US);

Nadezhda German, Amarillo, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 205/04 (2006.01); A61P 25/30 (2006.01); C07C 275/38 (2006.01); C07D 207/335 (2006.01); C07D 211/38 (2006.01); C07D 213/643 (2006.01); C07D 215/12 (2006.01); C07D 239/26 (2006.01); C07D 295/135 (2006.01); C07D 333/20 (2006.01); C07D 487/08 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07C 275/38 (2013.01); A61P 25/30 (2018.01); C07D 205/04 (2013.01); C07D 207/335 (2013.01); C07D 211/38 (2013.01); C07D 213/643 (2013.01); C07D 215/12 (2013.01); C07D 239/26 (2013.01); C07D 295/135 (2013.01); C07D 333/20 (2013.01); C07D 487/08 (2013.01); C07D 491/107 (2013.01);
Abstract

The present invention provides novel diarylurea derivatives (compounds of formula (I)) and their uses. The compounds of the present invention are demonstrated to be allosteric modulators of the CB1 receptor, and therefore useful for the treatment of diseases and conditions mediated by CB1.


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