The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Mar. 12, 2019
Applicant:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Inventors:
John M Maris, Philadelphia, PA (US);
Mark Yarmarkovich, Philadelphia, PA (US);
Assignee:
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 40/31 (2025.01); A61K 40/11 (2025.01); A61K 40/32 (2025.01); A61K 40/42 (2025.01); A61K 45/06 (2006.01); C12N 9/12 (2006.01); G01N 33/53 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 40/11 (2025.01); A61K 40/32 (2025.01); A61K 40/428 (2025.01); C12N 9/1241 (2013.01); G01N 33/5308 (2013.01); G01N 33/56977 (2013.01); A61K 2039/55522 (2013.01);
Abstract
The present disclosure provides methods and compositions for immunotherapy employing a modified T cell or NK cell comprising a receptor that binds to newly identified tumor antigens that can be administered to patients for disease (e.g., cancer) treatment. Also described are polynucleotides and vectors encoding the same.