The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Sep. 18, 2019
Applicant:
Albert-ludwigs-universitat Freiburg, Freiburg, DE;
Inventors:
Roland Schüle, Weisweil, DE;
Eric Metzger, Algolsheim, FR;
Sheng Wang, Freiburg, DE;
Manfred Jung, Gundelfingen, DE;
Nicolas Barthes, Blodelsheim, FR;
Bernhard Breit, Gundelfingen, DE;
Daad Sarraf, Freiburg, DE;
Tabea Pappert, Harxheim, DE;
Assignee:
Albert-Ludwigs-Universitat Freiburg, Freiburg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 31/437 (2006.01); A61K 31/519 (2006.01); A61K 31/7076 (2006.01); A61K 31/7105 (2006.01); A61P 35/00 (2006.01); C07K 16/40 (2006.01); C12N 9/10 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 39/001154 (2018.08); A61K 31/437 (2013.01); A61K 31/519 (2013.01); A61K 31/7076 (2013.01); A61K 31/7105 (2013.01); A61P 35/00 (2018.01); C07K 16/40 (2013.01); C12N 9/1007 (2013.01); C12N 15/1137 (2013.01); A61K 2039/505 (2013.01); C12N 2310/14 (2013.01);
Abstract
The present invention is inter alia concerned with an inhibitor selected from the group consisting of a selective KMT9-inhibitor, a selective METTL21A-inhibitor and a selective METTL21B-inhibitor for use in the treatment of cancer. KMT9, METTL21A and METTL21B are characterized herein for the first time as histone methyl transferases, and inhibitors of the same can be used for treating cancer.