The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Jan. 02, 2023
Applicants:
Nationwide Children's Hospital, Inc., Columbus, OH (US);
Ohio State Innovation Foundation, Columbus, OH (US);
Inventors:
Brian K. Kaspar, Westerville, OH (US);
Kevin Foust, Columbus, OH (US);
Assignees:
NATIONWIDE CHILDREN'S HOSPITAL, INC., Columbus, OH (US);
OHIO STATE INNOVATION FOUNDATION, Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 9/00 (2006.01); A61K 35/76 (2015.01); A61K 48/00 (2006.01); A61P 25/00 (2006.01); C07K 14/47 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/76 (2013.01); A61K 9/0019 (2013.01); A61K 9/0085 (2013.01); A61P 25/00 (2018.01); C07K 14/4702 (2013.01); C12N 7/00 (2013.01); C12N 2750/14132 (2013.01); C12N 2750/14143 (2013.01);
Abstract
Methods and materials for intrathecal delivery of recombinant Adeno-associated virus 9 (rAAV9) encoding Methyl-CpG binding protein 2 (MECP2) are provided. Use of the methods and materials is contemplated, for example, for the treatment of Rett syndrome.