The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Apr. 11, 2023
Applicant:

Hyloris Developments SA, Liège, BE;

Inventor:

Atul Patil, Liège, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/19 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 31/616 (2006.01);
U.S. Cl.
CPC ...
A61K 31/616 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01);
Abstract

The present invention provides a two-component drug delivery system for intravenous administration of an aqueous and sterile acetylsalicylic acid composition comprising: a first and second component which are physically separated, wherein the first component comprises a therapeutically effective amount of an acetylsalicylic acid; wherein the second component has a pH of 5.0 to 11.0 comprising an aqueous buffer solution; and providing a buffered aqueous solution of acetylsalicylic acid with a pH of 6.0-8.0 upon mixing, wherein said first component comprises a sterile spray dried or a sterile 20-90 kGy gamma irradiated, or an autoclaved terminally sterilized acetyl salicylic acid particulate powder; with the proviso that arginine, lysine, glutamic acid and betaine are excluded. The invention also provides drug delivery devices comprising the two-component drug delivery system, use of the system and devices in acetyl salicylic acid treatment of patients in need thereof and methods of manufacturing.


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