The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Dec. 30, 2022
Applicants:

University of Florida Research Foundation, Incorporated, Gainsville, FL (US);

Amilyfe, Llc, Norwood, MA (US);

Inventors:

Sadasivan Vidyasagar, Gainsville, FL (US);

Astrid Grosche, Gainsville, FL (US);

Xiaodong Xu, Gainsville, FL (US);

Shanshan Lin, Gainsville, FL (US);

Samuel Cheuvront, Norwood, MA (US);

Robert Kenefick, Norwood, MA (US);

Stephen Gatto, Norwood, MA (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 45/06 (2006.01); A61P 1/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 45/06 (2013.01); A61P 1/00 (2018.01);
Abstract

Formulations comprising particular free amino acids useful for promoting hydration and/or intestinal barrier function in a subject in need thereof are described herein. Such formulations and methods using same are useful for promoting hydration and/or intestinal barrier function in a subject in need thereof. Such subjects may be healthy, but in need of a formulation that promotes rapid hydration (e.g., within 15-90 minutes post-administration) or promotes intestinal barrier function; or such subjects may be afflicted by a disorder or disease associated with dehydration or impaired intestinal barrier function, respectively. Use of amino acid formulations described herein for promoting hydration and/or intestinal barrier function in a subject in need thereof, for the treatment of disorders or diseases associated dehydration and/or impaired intestinal barrier function, and in the preparation of a medicament for the treatment of disorders or diseases associated with dehydration and/or impaired intestinal barrier function are encompassed herein.


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