The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Jan. 26, 2022
Applicant:
Jazz Pharmaceuticals Research Uk Limited, Sittingbourne, GB;
Inventors:
Assignee:
JAZZ PHARMACEUTICALS RESEARCH UK LIMITED, Sittingbourne, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/05 (2006.01); A61K 31/19 (2006.01); A61K 31/352 (2006.01); A61K 31/4015 (2006.01); A61K 31/515 (2006.01); A61K 36/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/05 (2013.01); A61K 31/19 (2013.01); A61K 31/352 (2013.01); A61K 31/4015 (2013.01); A61K 31/515 (2013.01); A61K 36/00 (2013.01); A61K 45/06 (2013.01);
Abstract
The invention relates to the use of cannabidiol (CBD), at a dose of greater than 300 mg/day, in combination with a standard anti-epileptic drug (SAED) which acts via sodium or calcium channels, for use in the treatment of epilepsy. The SAED is preferably one which •modities low-threshold or transient neuronal calcium currents, or •reduces high-frequency neuronal firing and sodium-dependent action potentials and enhances GABA effects. Preferred SAEDs are ethosuximide and valproate.