The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2025
Filed:
Nov. 02, 2018
Applicant:
The Trustees of Princeton University, Princeton, NJ (US);
Inventors:
Robert K. Prud'homme, Princeton, NJ (US);
Kurt D. Ristroph, Princeton, NJ (US);
Nathalie M. Pinkerton, Princeton, NJ (US);
Hoang D. Lu, Princeton, NJ (US);
Paradorn Rummaneethorn, Princeton, NJ (US);
Assignee:
The Trustees of Princeton University, Princeton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 31/5377 (2006.01); A61K 31/7036 (2006.01); A61K 38/10 (2006.01); A61K 38/12 (2006.01); A61K 38/38 (2006.01); A61K 38/47 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5153 (2013.01); A61K 9/5161 (2013.01); A61K 9/5192 (2013.01); A61K 31/5377 (2013.01); A61K 31/7036 (2013.01); A61K 38/10 (2013.01); A61K 38/12 (2013.01); A61K 38/38 (2013.01); A61K 38/47 (2013.01);
Abstract
Methods for encapsulating water-soluble biologic and small molecule active pharmaceutical ingredients (APIs) into nanoparticles by applying nanoprecipitation techniques and ion-pairing the nanoparticles with hydrophobic counterions to produce new API salts that exhibit altered solubilities are presented.