The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

Mar. 29, 2024
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Christopher F. Reiche, Salt Lake City, UT (US);

Florian Solzbacher, Salt Lake city, UT (US);

Navid Farhoudi, Salt Lake City, UT (US);

Steven M. Blair, Salt Lake City, UT (US);

Jules J. Magda, Salt Lake City, UT (US);

Lars B. Laurentius, Cottonwood Heights, UT (US);

Prattay Deepta Kairy, Salt Lake City, UT (US);

Assignee:

University of Utah Research Foundation, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 8/00 (2006.01); G10K 11/04 (2006.01);
U.S. Cl.
CPC ...
A61B 8/4272 (2013.01); A61B 8/4483 (2013.01); A61B 8/5207 (2013.01); G10K 11/04 (2013.01); A61B 2562/0204 (2013.01); A61B 2562/028 (2013.01);
Abstract

Systems and methods for measuring changes in smart hydrogel microresonator structures positioned in an in vivo or other environment, having an acoustic resonance frequency in an ultrasound range. The system includes a smart hydrogel microresonator structure positioned within the environment configured to exhibit a change in resonance frequency in response to interaction with one or more predefined analytes in the environment. The system includes an ultrasound transducer for querying the smart hydrogel microresonator structure at or near its resonance frequency. The system also includes a computer system configured to receive ultrasound data as provided by query of the smart hydrogel microresonator structure and to determine changes in resonance frequency, amplitude or intensity of the ultrasound query wave, or mean grayscale value (MGV) associated with the ultrasound data of the smart hydrogel microresonator structure due to the change in resonance frequency. Such change can be correlated to concentration of the analyte.


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