The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2025

Filed:

May. 20, 2022
Applicant:

Abelzeta Inc., Rockville, MD (US);

Inventors:

Fei Wang, Shanghai, CN;

Jiaping He, Shanghai, CN;

Dijun Zhao, Shanghai, CN;

Victor Liu, Shanghai, CN;

Dingzhu Yang, Shanghai, CN;

Assignee:

ABELZETA INC., Rockville, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 1/125 (2025.01); A01N 1/126 (2025.01); A61K 39/00 (2006.01); C07K 14/765 (2006.01); C12N 5/00 (2006.01); C12N 5/0775 (2010.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A01N 1/125 (2025.01); A01N 1/126 (2025.01); A61K 39/0011 (2013.01); C07K 14/765 (2013.01); C12N 5/0037 (2013.01); C12N 5/0636 (2013.01); C12N 5/0663 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); C12N 2500/16 (2013.01); C12N 2500/32 (2013.01); C12N 2500/35 (2013.01); C12N 2500/38 (2013.01); C12N 2500/50 (2013.01); C12N 2500/62 (2013.01);
Abstract

Provided in the present invention is a cell freezing medium for clinical use. In particular, the cell freezing medium of the present invention comprises the following components: (1) human albumin; (2) cryoprotectant: the cryoprotectant comprises a combination of one or more of dimethyl sulfoxide, glycerol, and ethylene glycol; (3) a saline buffer; wherein the salt buffer is a solution containing Na, K, Mg, Cl, and CHCOOions; (4) a vitamin; and (5) an amino acid, wherein the human albumin concentration is 1%-20% (w/v). The cell, after long-term cryopreservation with the freezing medium of the present invention, has a high viability, and the cellular efficiency maintains a high uniformity. The grade of purity of the freezing medium of the present invention is the pharmaceutical grade or USP grade; and the freezing medium is safe and reliable for clinical use, and can be used or conventional adherent and suspension cells.


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