The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Dec. 15, 2022
Applicant:

United States of America As Represented BY the Administrator of Nasa, Washington, DC (US);

Inventors:

George Nehmetallah, Washington, DC (US);

Shahid Aslam, Washington, DC (US);

Thuc Phan, Washington, DC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G02B 21/36 (2006.01); G02B 21/08 (2006.01); G02B 21/14 (2006.01); G06T 3/4046 (2024.01); G06T 3/4053 (2024.01);
U.S. Cl.
CPC ...
G02B 21/365 (2013.01); G02B 21/086 (2013.01); G02B 21/14 (2013.01); G06T 3/4046 (2013.01); G06T 3/4053 (2013.01);
Abstract

Imaging devices, methods, and systems are disclosed. The disclosure includes a Fourier Ptychographic Microscope ('FPM') compatible for integration to a Microfluidic Device (“MD”) to perform wide Field-of-View (“FoV”), high spatial resolution imaging (<1 μm), for biosignature detection and motility in liquid samples, for use, without limitation, as a space-based payload. Fourier ptychography (“FP”) algorithms adapted for reconstruction are disclosed. A processor board and camera combined with FP algorithms adapted for reconstruction are used to computationally reconstruct sub-micron resolution images. In certain embodiments, a dual-modality portable FPM performs wide FoV, high lateral and axial resolution imaging, and high-resolution birefringence imaging, for biosignature detection and motility in liquid samples. Various combinations of the disclosed devices, methods, and systems may be employed, depending on the particular requirements of each implementation.


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