The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Apr. 03, 2020
Applicant:

University of Utah Research Foundation, Salt Lake City, UT (US);

Inventors:

Katherine (k-t) E. Varley, Salt Lake City, UT (US);

Rachel L. Stewart, Lexington, KY (US);

Philip S. Bernard, Salt Lake City, UT (US);

Katherine Updike, Salt Lake City, UT (US);

Assignee:

UNIVERSITY OF UTAH RESEARCH FOUNDATION, Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57415 (2013.01); G01N 33/57484 (2013.01);
Abstract

Disclosed herein are biomarkers and methods of using the same for determining the risk of recurrence of cancer in a subject. The methods may include determining the level of expression of at least one MHCII gene, determining the level of expression of at least one TIL gene, and determining an Immune Activation Score for the subject. Further provided are methods of diagnosing a subject with triple-negative breast cancer (TNBC) as having TNBC Basal-like subtype, and methods of treating cancer in a subject.


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