The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Dec. 04, 2017
Applicants:

University of Maryland, College Park, College Park, MD (US);

University of Maryland, Baltimore, Baltimore, MD (US);

Inventors:

Eunkyoung Kim, Woodstock, MD (US);

Gregory F. Payne, Hunt Valley, MD (US);

Mijeong Kang, Rockville, MD (US);

Reza Ghodssi, Potomac, MD (US);

Thomas E. Winkler, Greenbelt, MD (US);

George Banis, Silver Spring, MD (US);

Christopher Kitchen, Ellicott City, MD (US);

Deanna L. Kelly, York, PA (US);

William E. Bentley, Annapolis, MD (US);

Assignees:

UNIVERSITY OF MARYLAND, COLLEGE PARK, College Park, MD (US);

University of Maryland, Baltimore, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 33/49 (2006.01);
U.S. Cl.
CPC ...
G01N 27/3277 (2013.01); G01N 33/49 (2013.01);
Abstract

Methods are provided that allow global access to redox-based molecular information by coupling electrochemical measurements with signal processing approaches. More specifically, the disclosure provides methods that rely on the use of redox probes to assay samples for redox activities that act to exchange electrons with the probe thereby generating detectable optical and electrochemical signature signals that can then be assigned to a sample feature of interest. In particular embodiments, the disclosed assay methods are useful for diagnosis and prognosis of disorders, such as schizophrenia, that are found to be associated with a specific redox-based signature within a subject sample.


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