The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Feb. 29, 2024
Applicant:

Rules-based Medicine Inc., Austin, TX (US);

Inventors:

Andrew Raymon Morton Bradbury, Santa Fe, NM (US);

Michael Frank Erasmus, Santa Fe, NM (US);

Andre Teixeira, Santa Fe, NM (US);

Assignee:

RULES-BASED MEDICINE INC., Austin, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C12N 15/10 (2006.01); C12N 15/81 (2006.01); C40B 40/08 (2006.01); C40B 50/06 (2006.01);
U.S. Cl.
CPC ...
C40B 40/10 (2013.01); C12N 15/1037 (2013.01); C12N 15/81 (2013.01); C40B 40/08 (2013.01); C40B 50/06 (2013.01);
Abstract

Antibody libraries comprising a plurality of heavy chain variable domains and/or a plurality of light chain variable domains, which comprise complementary determining regions (CDRs) found in naturally-occurring human antibodies, and methods of making such antibody libraries. The antibody libraries are free of members that comprise one or more liabilities affecting one or more features of such members. Further, the antibody libraries comprise members having heavy chain and/or light chain CDRs not found in the same naturally-occurring human antibody.


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