The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Aug. 28, 2020
Applicant:
University of Dundee, Dundee, GB;
Inventors:
Assignee:
University of Dundee, Dundee, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/48 (2006.01); C12N 9/00 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/48 (2013.01); C12N 9/104 (2013.01); G01N 2333/9108 (2013.01);
Abstract
The present invention is directed to the development of novel photocrosslinking activity based probes (ABPs) and their uses. Specifically, ubiquitin-charged E2 conjugating enzymes are engineered and shown to be effective ABPs of RING ubiquitin E1 and E3 ligases as well as deubiquitination enzymes.