The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Sep. 13, 2021
Applicant:
Omrix Biopharmaceuticals Ltd., Rehovot, IL;
Inventors:
Assignee:
Omrix Biopharmaceuticals Ltd., Kiryat-Ono, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/74 (2006.01); C07K 14/745 (2006.01); C12Q 1/56 (2006.01); G01N 33/49 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6429 (2013.01); C07K 14/745 (2013.01); C12Q 1/56 (2013.01); G01N 33/491 (2013.01); A61K 38/00 (2013.01); C12Y 304/21005 (2013.01); G01N 2333/96463 (2013.01);
Abstract
Provided is a method for purifying α-thrombin and for quantifying α-thrombin and its degradation polypeptides in a liquid proteinatious solution. The method employs a one-step anion exchange chromatography method. The method allows purification and/or quantification of a homogenous post-translationally modified α-thrombin. The method can also be used for purification and/or quantification of β-thrombin.