The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Jun. 26, 2024
Genmab A/s, Valby, DK;
Bart E.c.g. De Goeij, Maarssen, NL;
Ilse Jongerius, De Bilt, NL;
Grietje Andringa, Utrecht, NL;
Madelon Paauwe, The Hague, NL;
Theodorus Sjouke Plantinga, Duiven, NL;
David Satijn, Nieuwegein, NL;
Jamila Laoukili, Zeist, NL;
Onno Wouter Kranenburg, Zeist, NL;
Marije Overdijk, Utrecht, NL;
GENMAB A/S, Valby, DK;
Abstract
The present invention relates to a multispecific antibody comprising at least a FAPα binding region comprising a first heavy chain variable region and a first light chain variable region; and a DR4 binding region comprising a second heavy chain variable region and a second light chain variable region. The invention further provides pharmaceutical compositions comprising the antibodies and use of the antibodies for therapeutic and diagnostic procedures, in particular in cancer therapy.