The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
May. 03, 2022
Applicant:
Berlin-chemie Ag, Berlin, DE;
Inventors:
Monica Binaschi, Rome, IT;
Mario Bigioni, Rome, IT;
Giuseppe Merlino, Rome, IT;
Cecilia Simonelli, Florence, IT;
Francesco Bertoni, Bellinzona, CH;
Andrea Pellacani, Florence, IT;
Assignee:
BERLIN-CHEMIE AG, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/519 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2851 (2013.01); A61K 31/519 (2013.01); A61K 47/68033 (2023.08); A61K 47/6849 (2017.08); A61P 35/00 (2018.01); C07K 16/2887 (2013.01);
Abstract
The present disclosure relates generally to the fields of immunology and molecular biology. More specifically, provided herein are pharmaceutical combinations comprising (A) antibodies, or antigen-binding portions thereof, directed against LY75, and (B) a second anti-cancer entity; nucleic acids encoding antibody combinations; methods for preparing antibody combinations; and methods for the treatment of diseases, such as cancers mediated by LY75 expression or activity.