The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Sep. 22, 2023
Applicant:

Marengo Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Seng-Lai Tan, Sudbury, MA (US);

Brian Edward Vash, Cambridge, MA (US);

Jonathan Hsu, Waltham, MA (US);

Dilini Charmain Gunasekera, Cambridge, MA (US);

Sangeetha Sagar Palakurthi, East Walpole, MA (US);

Andreas Loew, Boston, MA (US);

Assignee:

Marengo Therapeutics, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 35/17 (2025.01); A61K 39/00 (2006.01); A61K 40/10 (2025.01); A61K 40/11 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C12N 5/078 (2010.01);
U.S. Cl.
CPC ...
C07K 16/2809 (2013.01); A61K 35/17 (2013.01); A61K 40/10 (2025.01); A61K 40/11 (2025.01); A61K 40/4211 (2025.01); A61K 40/4215 (2025.01); A61P 35/00 (2018.01); C07K 16/2803 (2013.01); C07K 16/283 (2013.01); C07K 16/2878 (2013.01); C12N 5/0634 (2013.01); A61K 2039/505 (2013.01); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C07K 2317/92 (2013.01);
Abstract

The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.


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