The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Aug. 07, 2020
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);
Lawrence L. K. Leung, Hillsborough, CA (US);
Michael J. Morser, San Francisco, CA (US);
Timothy Myles, Sunnyvale, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
The United States Government as represented by the Department of Veterans Affairs, Washington, DC (US);
Abstract
Therapeutic antibodies specific for osteopontin and methods of using them for treating osteopontin-associated disorders are provided. In particular, antibodies, or antigen-binding fragments thereof, that inhibit thrombin-cleavage of osteopontin or block the activity of thrombin cleavage fragments of osteopontin are provided. Additionally, antibody conjugates and pharmaceutical compositions or formulations comprising the antibodies or antibody conjugates as well as kits including the antibodies, conjugates, or formulations are also provided.