The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Mar. 27, 2020
Applicants:
Orionis Biosciences, Inc., Waltham, MA (US);
Orionis Biosciences Bv, Zwijnaarde, BE;
Inventors:
Nikolai Kley, Waltham, MA (US);
Erik Depla, Zwijnaarde, BE;
Lennart Zabeau, Zwijnaarde, BE;
Jan Tavernier, Zwijnaarde, BE;
Assignees:
Orionis Biosciences, Inc., Waltham, MA (US);
Orionis Biosciences BV, Zwijnaarde, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/56 (2006.01); A61K 38/00 (2006.01); A61P 35/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/56 (2013.01); A61P 35/00 (2018.01); C07K 14/001 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
The present invention relates, in part, to chimeric protein complexes including an anti-Clec9A targeting moiety, a modified Fc domain, and a modified human IFNα and their use as therapeutic agents. The present invention further relates to pharmaceutical compositions comprising the chimeric protein complexes and their use in the treatment of various diseases.