The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 08, 2025

Filed:

Sep. 06, 2023
Applicant:

Tng Pharmaceuticals, Inc., Louisville, KY (US);

Inventors:

Kent R. Van Kampen, Payson, UT (US);

Serge Martinod, Groton, CT (US);

Assignee:

GNT Pharmaceuticals, Inc., Louisville, KY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43577 (2013.01); A61K 39/0003 (2013.01); A61K 39/00 (2013.01); A61K 2039/552 (2013.01); A61K 2039/575 (2013.01); C07K 2319/24 (2013.01); C07K 2319/40 (2013.01);
Abstract

Disclosed herein are fusion proteins comprising a truncated thrombostasin protein having at least 85% sequence homology to a thrombostasin protein, wherein the thrombostasin protein has a carboxy terminal deletion; and a fusion partner protein that is a non-thrombostasin protein. Further disclosed are vaccine compositions thrombostasin proteins having a comprising a carboxy terminal deletion, and methods for inhibiting a response to a thrombostasin protein in a host in need thereof, comprising the disclosed fusion proteins or vaccine compositions. Further disclosed are methods for the preparation of a fusion protein composition.


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